(d(CH₂)₅¹,Tyr(Me)²,Dab⁵,Arg⁸)-Vasopressin

β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Phe-Gln-Dab-Cys-Pro-Arg-Gly-NH₂ (Disulfide bond)

Placeholder

Product Number: 4145234

CAS Number: 176714-12-8

 224.70

Pack size available

1mg

Please select pack size:

Product Description

The isosteric substitution of Asn5 by Dab in oxytocin, vasopressin and their analogs invariably leads to a dramatic loss of the biolical activities of the peptides. In OT or VP antagonists, the exchange generates highly selective and potent OT and V1a receptor antagonists.

L.T.Parreiras-e-Silva et al., Proc. Natl. Acad. Sci. USA, 114, 9044 (2017)

Salt form: Trifluoroacetate

Molecular weight: 1137.38

Chemical Formula: C₅₂H₇₆N₁₄O₁₁S₂

Storage Temperature: < -15°C

Synonyms: d(CH2)5[Tyr(Me)2,Dab5]-AVP

Source: Synthetic

Country

Inquiry List

No products in the list