Prolamin (31-49)

Prolamins are the main components of gluten. They contribute to the cohesiveness and extensibility and storage of the gluten. Their high content in proline and glutamine makes them water-insoluble and difficult to digest in the gastrointestinal tract. Partial digestion generates peptide sequences which trig-ger immune responses in celiac and gluten-sensitive patients. This short sequence of prolamin, which corresponds to the Gln and Pro rich fraction, is involved in coeliac disease.