Furin Inhibitor II

H-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH₂

Product Number: 4061351

CAS Number: 673202-67-0

€ 86.70 – € 346.70

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Product Description

Hexa-D-arginine amide is a potent furin inhibitor with a Ki of 0.106 μM. It also inhibited the related convertases PACE4 and prohormone convertase-1 (PC1) with Ki values of 0.58 μM and 13 μM, respectively. The stable hexapeptide exhibited protection against anthrax toxemia in vitro and in vivo.

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Correction for Simonin et al., RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia

Erratum: F.Simonin et al., Proc. Natl. Acad. Sci. USA, 103, 16058 (2006)

A.Cameron et al., J. Biol. Chem., 275, 36741 (2000)

Salt form: Trifluoroacetate

Molecular weight: 954.16

Sum Formula: C₃₆H₇₅N₂₅O₆

Storage Temperature: < -15°C

Synonyms: Hexa-D-arginine amide

One Letter code: rrrrrr -NH₂

Source: Synthetic

Old Product Number: N-2000

Inhibitors
Furin

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