(Ala¹³)-Apelin-13 (human, bovine, mouse, rat) (Salt form trifluoroacetate)

H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH

Product Number: 4050032

CAS Number: 568565-11-7

€ 107 – € 428

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Product Description

Specific anatagonist of apelin-13. Systemic administration of Apelin-13 F13A (30 µg/kg) abolished the blood pressure-lowering effects of apelin-13 (15 µg/kg) in hypertensive rats.

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Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release.

N.De Mota et al., Proc. Natl. Acad. Sci. USA, 101, 10464 (2004)

Modification of the terminal residue of apelin-13 antagonizes its hypotensive action.

D.K.Lee et al., Endocrinology, 146, 231 (2005)

Salt form: Trifluoroacetate

Molecular weight: 1474.75

Chemical Formula: C₆₃H₁₀₇N₂₃O₁₆S

Storage Temperature: < -15°C

One Letter code: QRPRLSHKGPMPA

Source: Synthetic

Old Product Number: H-6308

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