(D-Ser(tBu)⁶,Azagly¹⁰)-LHRH

Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH₂

Product Number: 4038252

CAS Number: 145781-92-6

€ 88.80 – € 356.30

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Product Description

Goserelin acetate, a synthetic peptide analog of LHRH, is used in the treatment of prostate cancer, advanced breast cancer and in the management of endometriosis. CAS Number (Goserelin net): 65807-02-5.

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Peptides In Veterinary Peptides Medicine
A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses.

D.C.Jackson et al., Proc. Natl. Acad. Sci. USA, 101, 15440 (2004)

Luteinizing hormone-releasing hormone agonist limits DU-145 prostate cancer growth by attenuating epidermal growth factor receptor signaling.

A.Wells et al., Clin. Cancer Res., 8, 1251 (2002)

Use of goserelin in the treatment of breast cancer.

A.Rody et al., Expert Rev. Anticancer Ther., 5, 591 (2005)

Goserelin acetate in combination with radiotherapy for prostate cancer.

M.Roach 3rd and A.Izaguirre, Expert Opin. Pharmacother., 8, 257 (2007)

No supra-additive effects of goserelin and radiotherapy on clonogenic survival of prostate carcinoma cells in vitro.

, Merck Index, 15th ed., No. 4562, (2013)

R.M.Herrmann et al., Radiat Oncol, 2, 31 (2007)

Salt form: Acetate

Molecular weight: 1269.43

Chemical Formula: C₅₉H₈₄N₁₈O₁₄

Storage Temperature: < -15°C

Synonyms: Goserelin

Source: Synthetic

Old Product Number: H-6395

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