(Ala¹)-PAR-4 (1-6) amide (mouse)

H-Ala-Tyr-Pro-Gly-Lys-Phe-NH₂

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Product Number: 4035529

CAS Number: 352017-71-1

CHF 89.90 – CHF 1,438.10

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Product Description

The peptide AYPGKF-amide based on the proteolytically-revealed tethered ligand sequence of the murine proteinase-activated receptor-4 (PAR-4) was shown to cause platelet aggregation with an EC₅₀ value of about 15 µM.

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The aspartimide problem in Fmoc-based SPPS. Part I.

M.Mergler et al., J. Pept. Sci., 9, 36 (2003)

PAR-4 agonist AYPGKF stimulates thromboxane production by human platelets.

R.A.Henriksen and V.K.Hanks, Arterioscler. Thromb. Vasc. Biol., 22, 861 (2002)

Structure-function analysis of protease-activated receptor 4 tethered ligand peptides. Determinants of specificity and utility in assays of receptor function.

T.R.Faruqi et al., J. Biol. Chem., 275, 19728 (2000)

Salt form: Trifluoroacetate

Molecular weight: 680.8

Chemical Formula: C₃₄H₄₈N₈O₇

Storage Temperature: < -15°C

Synonyms: (Ala¹)-Thrombin Receptor-Like 3 (1-6) amide (mouse)

One Letter code: AYPGKF-NH₂

Source: Synthetic

Old Product Number: H-6046

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