Amyloid β-Protein (17-40)

H-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH

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Product Number: 4034233

CAS Number: 156790-69-1

€ 138 – € 238.60

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Product Description

Cleavage of APP by alpha- and gamma-secretase (i.e. the non-amyloidogenic pathway) yields p3 peptide, a mix of Aβ 17-40 and Aβ 17-42. p3 is a major constituent of diffuse plaques observed in AD brains and pre-amyloid plaques in people affected by Down syndrome.

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Amyloid Beta Peptides & Alzheimer's Disease
Prevention of diseases caused by Staphylococcus aureus using the peptide RIP.

N.Balaban et al., Peptides, 21, 1301 (2000)

Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome.

H.Jang et al., Proc. Natl. Acad. Sci. USA, 107, 6538 (2010)

Peptide p3 may play a neuroprotective role in the brain.

W.Han et al., Med. Hypotheses, 76, 543 (2011)

Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome.

H.Jang et al., Proc. Natl. Acad. Sci. USA, 107, 6538 (2010)

Peptide p3 may play a neuroprotective role in the brain.

W.Han et al., Med. Hypotheses, 76, 543 (2011)

Salt form: Ammonium

Molecular weight: 2392.85

Chemical Formula: C₁₁₀H₁₇₈N₂₆O₃₁S

Storage Temperature: < -15°C

Synonyms: β-Amyloid (17-40)

One Letter code: LVFFAEDVGSNKGAIIGLMVGGVV

Source: Synthetic

Old Product Number: H-7532

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