Fmoc-Glu(EDANS)-OH

Fmoc-Glu(EDANS)-OH

Product Number: 4033590

CAS Number: 193475-66-0

€ 375.60 – € 668.80

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Product Description

Building block for the synthesis of internally quenched fluorogenic peptide substrates (FRET substrates). The fluorescent group EDANS can be efficiently quenched by the nonfluorescent DABCYL chromophore.

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Proteolytic activation of recombinant pro-memapsin 2 (pro-beta-secretase) studied with new fluorogenic substrates.

J.Ermolieff et al., Biochemistry, 39, 12450 (2000)

A general method for the preparation of internally quenched fluorogenic protease substrates using solid-phase peptide synthesis.

L.L.Maggiora et al., J. Med. Chem., 35, 3727 (1992)

Molecular weight: 617.68

Chemical Formula: C₃₂H₃₁N₃O₈S

Storage Temperature: < -15°C

Old Product Number: B-3620

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