Calcitonin (salmon I)

H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH₂ (Disulfide bond)

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Product Number: 4033011

CAS Number: 47931-85-1

€ 107 – € 1,714.10

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Product Description

Calcitonin inhibits osteoclast activity, lowers the blood calcium level, and positively influences bone mass density. Salmon calcitonin (sCT) is more potent than the human analog. sCT may act as an amylin agonist (Wielinga et al.). In animal studies, administration of sCT was shown to reduce food intake.

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Effect of intraperitoneal CCK-8 on food intake and brain orexin-A after 48 h of fasting in the rat.

E.Gallmann et al., Regul. Pept., 133, 139 (2006)

Effects of intermittent intraperitoneal infusion of salmon calcitonin on food intake and adiposity in obese rats.

P.K.Chelikani et al., Am. J. Physiol. Regul. Integr. Comp. Physiol., 293, R1798 (2007)

The acute effect of amylin and salmon calcitonin on energy expenditure.

P.Y.Wielinga et al., Physiol. Behav., 91, 212 (2007)

Salmon calcitonin reduces food intake through changes in meal sizes in male rhesus monkeys.

N.T.Bello et al., Am. J. Physiol. Regul. Integr. Comp. Physiol., 295, R76 (2008)

Calcitonin therapy in osteoporosis.

M.Munoz-Torres et al., Treat. Endocrinol., 3, 117 (2004)

Degradation of salmon calcitonin in rat kidney and liver homogenates.

S.Liao et al., Pharmazie, 63, 743 (2008)

Molecular weight: 3431.9

Chemical Formula: C₁₄₅H₂₄₀N₄₄O₄₈S₂

Storage Temperature: < -15°C

Synonyms: Salmon Calcitonin

One Letter code: CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP-NH₂

Source: Synthetic

Old Product Number: H-2260

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