Somatostatin-14

H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bond)

Product Number: 4033009

CAS Number: 38916-34-6

€ 62.10 – € 249.30

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Product Description

Somatostatin-14 (SRIF) was originally isolated from ovine hypothalamic extracts on the basis of its ability to inhibit the secretion of radioimmunoassayable growth hormone by primary cultures of enzymatically dispersed rat anterior pituitary cells. SRIF is a small cyclic neuropeptide hormone with broad inhibitory effects on endocrine secretions such as the production of GH, glucagon, and insulin.

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Peptides in cancer research
D-penicillamine in systemic sclerosis? Yes!

T.A.Medsger Jr. et al., Scand. J. Rheumatol., 30, 192 (2001)

Spontaneous fibrillation of the native neuropeptide hormone Somatostatin-14.

W.van Grondelle et al., J. Struct. Biol., 160, 211 (2007)

Peptides that regulate food intake: somatostatin alters intake of amino acid-imbalanced diets and taste buds of tongue in rats.

G.Scalera, Am. J. Physiol. Regul. Integr. Comp. Physiol., 284, R1389 (2003)

Changes in thymus size, cellularity and relation between thymocyte subpopulations in young adult rats induced by somatostatin-14.

D.M.Petrovic-Dergovic et al., Neuropeptides, 41, 485 (2007)

Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone.

P.Brazeau et al., Science, 179, 77 (1973)

Somatostatin-14 influences pituitary-ovarian axis in peripubertal rats.

N.Nestorovic et al., Histochem. Cell Biol., 130, 699 (2008)

Somatostatin and growth hormone releasing factor: synthesis, location, metabolism and function.

A.Gomez-Pan and M.D.Rodriguez-Arnao, Clin. Endocrinol. Metab., 12, 469 (1983)

Molecular weight: 1637.9

Chemical Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Storage Temperature: < -15°C

Synonyms: SRIF

One Letter code: AGCKNFFWKTFTSC

Source: Synthetic

Old Product Number: H-1490

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