Osteostatin (human)

H-Thr-Arg-Ser-Ala-Trp-Leu-Asp-Ser-Gly-Val-Thr-Gly-Ser-Gly-Leu-Glu-Gly-Asp-His-Leu-Ser-Asp-Thr-Ser-Thr-Thr-Ser-Leu-Glu-Leu-Asp-Ser-Arg-OH

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Product Number: 4031194

CAS Number: 137348-10-8

€ 312.40 – € 561.80

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Product Description

The carboxyl-terminal fragment of pTHrP, TRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSR, is a potent inhibitor of osteoclastic bone resorption. It is suggested that this product acts directly on osteoclasts.

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Spatial and temporal expression of parathyroid hormone-related protein during wound healing.

E.A.G.Blomme et al., J. Invest. Dermatol., 112, 788 (1999)

A potent inhibitor of osteoclastic bone resorption within a highly conserved pentapeptide region of parathyroid hormone-related protein; PTHrP[107-111].

A.J.Fenton et al., Endocrinology, 129, 3424 (1991)

A carboxyl-terminal peptide from the parathyroid hormone-related protein inhibits bone resorption by osteoclasts.

A.J.Fenton et al., Endocrinology, 129, 1762 (1991)

A potent inhibitor of osteoclastic bone resorption within a highly conserved pentapeptide region of parathyroid hormone-related protein; PTHrP[107-111].

A.J.Fenton et al., Endocrinology, 129, 3424 (1991)

Salt form: Trifluoroacetate

Molecular weight: 3451.62

Chemical Formula: C₁₄₂H₂₂₈N₄₂O₅₈

Storage Temperature: < -15°C

Synonyms: Hypercalcemia of Malignancy Factor (107-139) (human)

One Letter code: TRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSR

Source: Synthetic

Old Product Number: H-3212

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