pTH-Related Protein (1-40) (human, mouse, rat)

H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-Glu-Ile-Arg-Ala-Thr-Ser-OH

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Product Number: 4031191

CAS Number: 120298-73-9

€ 267.50 – € 491.10

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Product Description

pTHrP (1-40) enhanced significantly, in a dose-related manner, the low Ca²⁺-stimulated pTH secretion in normal rats. Whitfield et al. observed that this pTHrP fragment stimulates membrane-associated protein kinase C activity in rat spleen lymphocytes.

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PTHrP enhances the secretory response of PTH to a hypocalcemic stimulus in rat parathyroid glands.

E.Lewin et al., Kidney Int., 58, 71 (2000)

Autoregulation in the parathyroid glands by PTH/PTHrP receptor ligands in normal and uremic rats.

E.Lewin et al., Kidney Int., 64, 63 (2003)

PTHrP enhances the secretory response of PTH to a hypocalcemic stimulus in rat parathyroid glands.

E.Lewin et al., Kidney Int., 58, 71 (2000)

PTHrP enhances the secretory response of PTH to a hypocalcemic stimulus in rat parathyroid glands.

E.Lewin et al., Kidney Int., 58, 71 (2000)

C-terminal fragments of parathyroid hormone-related protein, PTHrP-(107-111) and (107-139), and the N-terminal PTHrP-(1-40) fragment stimulate membrane-associated protein kinase C activity in rat spleen lymphocytes.

J.F.Whitfield et al., J. Cell. Physiol., 158, 518 (1994)

A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression.

L.J.Suva et al., Science, 237, 893 (1987)

Salt form: Trifluoroacetate

Molecular weight: 4675.34

Chemical Formula: C₂₀₇H₃₃₄N₆₆O₅₈

Storage Temperature: < -15°C

Synonyms: Hypercalcemia of Malignancy Factor (1-40) (human, mouse, rat)

One Letter code: AVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATS

Source: Synthetic

Old Product Number: H-6810

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