H-α-Difluoro-Me-DL-Orn-OH · HCl · H₂O

H-α-Difluoro-Me-DL-Orn-OH · HCl · H₂O

Product Number: 4030547

CAS Number: 96020-91-6

 62.10 535

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Product Description

α-Difluoromethylornithine is a suicide inhibitor of ornithine decarboxylase. Initially developed for cancer treatment, eflornithine was found to be very efficient against trypanosomiasis. The ornithine derivative also found use in cosmetics, eflornithine-containing creams allow to reduce excessive hair growth (hirsutism). CAS Number (net): 67037-37-0, (hydrochloride): 68278-23-9.

C.Carrillo et al., Biochem. Biophys. Res. Commun., 279, 663 (2000)

C.Burri and R.Brun, Parasitol. Res., 90 Supp. 1, S49 (2003)

F.L.Meyskens and E.W.Gerner, Clin. Cancer Res., 5, 945 (1999)

A.Lipton et al., Cancer, 63, 433 (1989)

Molecular weight: 236.65

Sum Formula: C₆H₁₂F₂N₂O₂ · HCl · H₂O

Storage Temperature: < -15°C

Synonyms: Eflornithine · HCl · H₂O

Old Product Number: F-2395

Inhibitors
Ornithine Decarboxylase

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