µ-Conotoxin GIIIA

H-Arg-Asp-Cys-Cys-Thr-Hyp-Hyp-Lys-Lys-Cys-Lys-Asp-Arg-Gln-Cys-Lys-Hyp-Gln-Arg-Cys-Cys-Ala-NH₂ (Disulfide bonds between Cys³ and Cys¹⁵/Cys⁴ and Cys²⁰/Cys¹⁰ and Cys²¹)

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Product Number: 4030525

CAS Number: 129129-65-3

€ 535 – € 892.40

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Product Description

µ-Conotoxin GIIIA from the Conus geographus L. venom blocks with very high selectivity the muscle subtype of sodium channels.

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A new Conus peptide ligand for mammalian presynaptic Ca2+ channels.

D.R.Hillyard et al., Neuron, 9, 69 (1992)

Conus geographus toxins that discriminate between neuronal and muscle sodium channels.

L.J.Cruz et al., J. Biol. Chem., 260, 9280 (1985)

mu-conotoxin GIIIA, a peptide ligand for muscle sodium channels: chemical synthesis, radiolabeling, and receptor characterization.

L.J.Cruz et al., Biochemistry, 28, 3437 (1989)

Molecular weight: 2609.08

Chemical Formula: C₁₀₀H₁₇₀N₃₈O₃₂S₆

Storage Temperature: < -15°C

Source: Synthetic

Old Product Number: H-2738

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