ω-Conotoxin MVIIC

H-Cys-Lys-Gly-Lys-Gly-Ala-Pro-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Arg-Gly-Lys-Cys-NH₂ (Disulfide bonds between Cys¹ and Cys¹⁶/Cys⁸ and Cys²⁰/Cys¹⁵ and Cys²⁶)

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Product Number: 4030522

CAS Number: 147794-23-8

€ 446.20 – € 713.70

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Product Description

Like ω-conotoxin GVIA, this Conus magus peptide inhibits presynaptic Ca²⁺ channels. However, ω-conotoxin MVIIC clearly inhibits additional Ca²⁺ channel subtypes in the mammalian central nervous system. Thus, it should become a standard pharmacological reagent for investigating synaptic transmission in the mammalian nervous system.

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Inactivation of chymotrypsin and human skin chymase: kinetics of time-dependent inhibition in the presence of substrate.

L.A.Johnson et al., Biochim. Biophys. Acta, 953, 269 (1988)

Effects of diverse omega-conopeptides on the in vivo release of glutamic and gamma-aminobutyric acids.

R.Newcomb and A.Palma, Brain Res., 638, 95 (1994)

A new Conus peptide ligand for mammalian presynaptic Ca2+ channels.

D.R.Hillyard et al., Neuron, 9, 69 (1992)

Effects of diverse omega-conopeptides on the in vivo release of glutamic and gamma-aminobutyric acids.

R.Newcomb and A.Palma, Brain Res., 638, 95 (1994)

Molecular weight: 2749.29

Chemical Formula: C₁₀₆H₁₇₈N₄₀O₃₂S₇

Storage Temperature: < -15°C

One Letter code: CKGKGAPCRKTMYDCCSGSCGRRGKC-NH₂

Source: Synthetic

Old Product Number: H-8835

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