Amyloid β-Protein (1-38)

H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-OH

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Product Number: 4030204

CAS Number: 131438-74-9

€ 94.20 – € 174.40

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Product Description

Like Aβ (25-35), the Aβ fragment (1-38) destabilizes calcium homeostasis and renders human cortical neurones vulnerable to environmental insults.

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Amyloid Beta Peptides & Alzheimer's Disease
An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P.

N.W.Kowall et al., Proc. Natl. Acad. Sci. USA, 88, 7247 (1991)

NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.

M.Yoshimoto et al., Proc. Natl. Acad. Sci. USA, 92, 9141 (1995)

Aβ38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models.

J.Reinert et al., J. Alzheimers Dis., 39, 871 (2014)

Salt form: Trifluoroacetate

Molecular weight: 4131.6

Chemical Formula: C₁₈₄H₂₇₇N₅₁O₅₆S

Storage Temperature: < -15°C

One Letter code: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGG

Source: Synthetic

Old Product Number: H-2966

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