Z-Val-Ala-Asn-AMC

Z-Val-Ala-Asn-AMC

Product Number: 4029129

CAS Number: 245036-58-2

€ 196.90 – € 784.30

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Product Description

Substrate for the determination of a new cysteine endopeptidase which is required for antigen processing. Z-VAN-AMC has been used as a fluorogenic substrate for porcine asparaginyl endopeptidase (AEP, legumain).

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Influence of caspase activity on micronuclei detection: a possible role for caspase-3 in micronucleation.

I.Decordier et al., Mutagenesis, 20, 173 (2005)

Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes.

T.Burster et al., J. Immunol., 172, 5495 (2004)

Characterization of legumain.

G.Schwarz et al., Biol. Chem., 383, 1813 (2002)

An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

B.Manoury et al., Nature, 396, 695 (1998)

Molecular weight: 593.64

Sum Formula: C₃₀H₃₅N₅O₈

Storage Temperature: < -15°C

One Letter code: Z-VAN-AMC

Source: Synthetic

Old Product Number: I-1840

Substrates
Legumain

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