Ac-Asp-Glu-Val-Asp-AFC

Ac-Asp-Glu-Val-Asp-AFC

Product Number: 4027914

CAS Number: 201608-14-2

CHF 269.60

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Product Description

Ac-DEVD-AFC is a sensitive fluorescent substrate for the assay of caspase-3 activity. The trifluoromethyl substituent of the fluorophore improves the membrane permeability of the substrate. CAS-Number (net) 141258-58-4 .

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Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease.

V.Hook et al., Biol. Chem., 386, 931 (2005)

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases.

J.Xiang et al., Proc. Natl. Acad. Sci. USA, 93, 14559 (1996)

Molecular weight: 729.62

Sum Formula: C₃₀H₃₄F₃N₅O₁₃

Storage Temperature: < -15°C

Synonyms: Ac-DEVD-AFC

One Letter code: Ac-DEVD-AFC

Source: Synthetic

Old Product Number: I-1725

Substrates
"Caspase-3 (CPP-32; Yama; Apopain)
Caspase-7 (ICE-LAP3; Mch3; CMH-1)"

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