MG 132

Z-Leu-Leu-Leu-aldehyde

Product Number: 4027888

CAS Number: 133407-82-6

CHF 224.70

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Product Description

Z-LLL-CHO (MG132) was shown to initiate neurite outgrowth in PC12 cells with an optimal concentration of 20 nM and to be a very strong inhibitor of 20S proteasome and of calpain.

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Peptides in cancer research
A review of commercially available thrombin generation assays

J.Kintigh et al., Res. Pract. Thromb. Haemost., 2, 42 (2017)

Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-leucine and tri-leucine.

S.Tsubuki et al., J. Biochem., 119, 572 (1996)

The structure-function relationship between peptide aldehyde derivatives on initiation of neurite outgrowth in PC12h cells.

Y.Saito et al., Neurosci. Lett., 120, 1 (1990)

Molecular weight: 475.63

Sum Formula: C₂₆H₄₁N₃O₅

Storage Temperature: < -15°C

Synonyms: MG 132

Source: Synthetic

Old Product Number: N-1635

Inhibitors
Calpain
Multicatalytic Endopeptidase Complex
Proteasome Endopeptidase Complex

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