Leptin (22-56) (human)

H-Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH

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Product Number: 4026665

CAS Number: 183598-56-3

€ 223.60 – € 401.30

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Product Description

After central administration of this leptin fragment by feeding in the rat inhibition of food intake was observed. Leptin (22-56) depolarized rat hypothalamic paraventricular nucleus neurons. This leptin fragment was shown to enhance the proliferative activity of both the normal myometrium and myoma cells in primary culture.

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Diabetes Peptides
Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor.

J.Gulyas et al., Proc. Natl. Acad. Sci. USA, 92, 10575 (1995)

A 35 amino acid fragment of leptin inhibits feeding in the rat.

W.K.Samson et al., Endocrinology, 137, 5182 (1996)

Leptin depolarizes rat hypothalamic paraventricular nucleus neurons.

J.E.Powis et al., Am. J. Physiol., 274, R1468 (1998)

Molecular weight: 3950.55

Chemical Formula: C₁₇₁H₂₉₈N₅₀O₅₆

Storage Temperature: < -15°C

Synonyms: Obese Gene Peptide (22-56) (human)

One Letter code: VPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQK

Source: Synthetic

Old Product Number: H-3424

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