Autocamtide-2-Related Inhibitory Peptide

H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH

Product Number: 4026616

CAS Number: 167114-91-2

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Product Description

AIP, non-phosphorylatable analog of autocamtide-2, was found to be a highly specific and potent inhibitor of calmodulin-dependent protein Kinase II (IC₅₀= 40 nM) without affecting cyclic AMP-dependent protein kinase, protein kinase C and calmodulin-dependent protein kinase IV.

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Protein-tyrosine phosphatase inhibition by a peptide containing the phosphotyrosyl mimetic, L-O-malonyltyrosine.

H.K.Kole et al., Biochem. Biophys. Res. Commun., 209, 817 (1995)

A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II.

A.Ishida et al., Biochem. Biophys. Res. Commun., 212, 806 (1995)

Salt form: Trifluoroacetate

Molecular weight: 1497.76

Sum Formula: C₆₄H₁₁₆N₂₂O₁₉

Storage Temperature: < -15°C

Synonyms: AIP

One Letter code: KKALRRQEAVDAL

Source: Synthetic

Old Product Number: H-3384

Inhibitors
Ca²⁺/Calmodulin-Dependent Protein Kinase

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