Neuromedin B

H-Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH₂

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Product Number: 4020211

CAS Number: 87096-84-2

€ 71.70 – € 1,141.70

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Product Description

NMB, a bombesin-linke peptide, binds to the bombesin receptors BRS1-4. NMB is expressed in the pituitary, brain, pancreas, adrenal and gastrointestinal tract. Its expression in adipose tissue appears to be regulated by changes in energy balance. NMB could inhibit food intake and modulates stress-related behavior.

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Diabetes Peptides

Galanin and galanin antagonists: molecular and biochemical perspectives.

T.Bartfai et al., Trends Pharmacol. Sci., 13, 312 (1992)

Influence of maternal educational level on the association between the rs3809508 neuromedin B gene polymorphism and the risk of obesity in the HELENA study.

M.Pigeyre et al., Int. J. Obes., 34, 478 (2010)

Effect of thyroid hormones on pituitary neuromedin B and possible interaction between thyroid hormones and neuromedin B on thyrotropin secretion.

T.M.Ortiga-Carvalho et al., Regul. Pept., 67, 47 (1996)

Stress and eating: a dual role for bombesin-like peptides.

Z.Merali et al., Front. Neurosci., 7, 193 (2013)

Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord.

N.Minamino et al., Biochem. Biophys. Res. Commun., 114, 541 (1983)

Expression of neuromedin B in adipose tissue and its regulation by changes in energy balance.

N.Hoggard et al., J. Mol. Endocrinol., 39, 199 (2007)

Salt form: Trifluoroacetate

Molecular weight: 1132.31

Chemical Formula: C₅₂H₇₃N₁₅O₁₂S

Storage Temperature: < -15°C

One Letter code: GNLWATGHFM-NH₂

Source: Synthetic

Old Product Number: H-3280

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