(Leu³¹,Pro³⁴)-Neuropeptide Y (porcine)

H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH₂

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Product Number: 4018713

CAS Number: 125580-28-1

€ 491.10

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Product Description

This NPY analog is a highly potent and selective ligand for Y₁ receptors in different cell lines and tissues. It has therefore been used to detect the NPY/PYY receptor subtype distribution, e.g., in rat brain. The peptide is also active in vivo, showing an even higher potency than NPY in increasing blood pressure in anesthetized rats.

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Diabetes Peptides
[Leu31-Pro34] neuropeptide Y identifies a subtype of 125I-labeled peptide YY binding sites in the rat brain.

A.M.L.Castrucci et al., Drugs Future, 15, 41 (1990)

[Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist.

D.R.Gehlert et al., Neurochem. Int., 21, 45 (1992)

[Leu31-Pro34] neuropeptide Y identifies a subtype of 125I-labeled peptide YY binding sites in the rat brain.

J.Fuhlendorff et al., Proc. Natl. Acad. Sci. USA, 87, 182 (1990)

D.R.Gehlert et al., Neurochem. Int., 21, 45 (1992)

Salt form: Trifluoroacetate

Molecular weight: 4222.69

Chemical Formula: C₁₉₀H₂₈₆N₅₄O₅₆

Storage Temperature: < -15°C

Synonyms: [Leu31, Pro34] Neuropeptide Y (1-36), porcine

One Letter code: YPSKPDNPGEDAPAEDLARYYSALRHYINLLTRPRY-NH₂

Source: Synthetic

Old Product Number: H-8575

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