Amyloid β-Protein (1-43)

H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-Thr-OH

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Product Number: 4018358

CAS Number: 134500-80-4

€ 281.40 – € 468.70

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Product Description

The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer’s disease and Down’s syndrome. Additionally it acts as an inhibitor of the ubiquitin-dependent protein degradation in vitro.

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Amyloid Beta Peptides & Alzheimer's Disease
Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides.

A.F.James et al., Cardiovasc. Drug Rev., 11, 253 (1993)

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state.

B.A.Yankner et al., Science, 250, 279 (1990)

Amyloid beta-protein inhibits ubiquitin-dependent protein degradation in vitro.

C.J.Pike et al., J. Neurosci., 13, 1676 (1993)

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease.

L.Gregori et al., J. Biol. Chem., 270, 19702 (1995)

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides.

D.Goldgaber et al., Science, 235, 877 (1987)

B.A.Yankner et al., Science, 250, 279 (1990)

Molecular weight: 4615.21

Chemical Formula: C₂₀₇H₃₁₈N₅₆O₆₂S

Storage Temperature: < -15°C

Synonyms: β-Amyloid (1-43)

One Letter code: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIAT

Source: Synthetic

Old Product Number: H-1586

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