Suc-Ala-Leu-Pro-Phe-pNA

Suc-Ala-Leu-Pro-Phe-pNA

Product Number: 4015254

CAS Number: 128802-78-8

€ 178.70 – € 713.70

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Product Description

Substrate for FK-506 binding proteins (FKBPs, also called macrophilins) and cyclophilins, which belong to the group of peptidyl prolyl cis-trans isomerases (PPIases). Suc-ALPF-pNA,has been used for an uncoupled protease-free assay of PPIase activity.

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Human leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors.

T.Tanaka et al., Biochemistry, 24, 2040 (1985)

Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2.

J.B.Nielsen et al., Proc. Natl. Acad. Sci. USA, 89, 7471 (1992)

Potency variation of small-molecule chymase inhibitors across species.

J.Kervinen et al., Biochem. Pharmacol., 80, 1033 (2010)

The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.

U.K.Jinwal et al., J. Neurosci., 30, 591 (2010)

FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity.

M.B.Cox et al., Mol. Endocrinol., 21, 2956 (2007)

Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay.

J.L.Kofron et al., Biochemistry, 30, 6127 (1991)

A protease-free assay for peptidyl prolyl cis/trans isomerases using standard peptide substrates.

B.Janowski et al., Anal. Biochem., 252, 299 (1997)

Molecular weight: 666.73

Sum Formula: C₃₃H₄₂N₆O₉

Storage Temperature: < -15°C

One Letter code: Suc-ALPF-pNA

Source: Synthetic

Old Product Number: L-1620

Substrates
Peptidylprolyl Isomerase

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