Amyloid β-Protein (12-28)

H-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH

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Product Number: 4014778

CAS Number: 107015-83-8

 80.30 321

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Product Description

Injection of the amyloid β-protein fragment VHHQKLVFFAEDVGSNK into different limbic system structures in mice impaired retention with remarkably similar efficacy and in a dose-dependent manner. Aβ (12-28) and other Aβ fragments may exert dysregulatory cognitive effects by incoordination of K⁺ channel function in neurons, glia and endothelial cells.

M.Zaoral et al., Coll. Czech. Chem. Commun., 32, 1242 (1967)

M.Sadowski et al., Am. J. Pathol., 165, 937 (2004)

Molecular weight: 1955.2

Chemical Formula: C₈₉H₁₃₅N₂₅O₂₅

Storage Temperature: < -15°C

Synonyms: Alzheimer's Disease β-Protein (12-28)

One Letter code: VHHQKLVFFAEDVGSNK

Source: Synthetic

Old Product Number: H-7910

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