TBTU

N-[(1H-Benzotriazol-1-yl)(dimethylamino)methylene]-N-methylmethanaminium tetrafluoroborate N-oxide

Product Number: 4013268

CAS Number: 125700-67-6

€ 71.70

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Product Description

TBTU is successfully used as coupling reagent in solid phase peptide synthesis. It acts as an excellent activating reagent causing low racemization during condensation of peptide segments. A study of the structure of TBTU in solid state as well as in solution by Abdelmoty et al. showed that the compound is a guanidinium N-oxide and not an uronium salt.

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The inhibitory effect of ACTH 1–10 on extinction of a conditioned avoidance response: Its independence of thyroid function.

D.De Wied and G.Pirie, Physiology & Behavior , 3, 355 (1968)

J.M.Matsoukas et al., J. Med. Chem., 39, 3585 (1996)

R.Knorr et al., Tetrahedron Lett., 30, 1927 (1989)

R.Knorr et al., Peptides 1988, Proceedings of the 20th European Peptide Symposium, Tuebingen, p. 37, G.Jung and E.Bayer, eds., W.de Gruyter, Berlin, (1989)

P.Henklein et al., Innovation and Perspectives in Solid Phase Synthesis and Combinatorial Libraries, 5th International Symposium, London, p. 309, R.Epton, ed., Mayflower Scientific (1998), ()

Molecular weight: 321.09

Chemical Formula: C₁₁H₁₆BF₄N₅O

Storage Temperature: +5 ± 3 °C

Synonyms: O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium-tetrafluoroborate

Old Product Number: Q-1665

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