ACTH (1-24) (human, bovine, rat)

H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH

Product Number: 4011958

CAS Number: 16960-16-0

€ 125.20 – € 499.70

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Product Description

Tetracosactide, a C-terminally truncated ACTH, still exhibits corticotropic activity, but it is less immunogenic than the full-length peptide hormone. The peptide induces an increase in the circulating level of glucocorticoids.

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Peptides In Veterinary Peptides Medicine
Natriuretic peptides: a new lipolytic pathway in human adipocytes.

C.Sengenes et al., FASEB J., 14, 1345 (2000)

Changes in cellular levels of cyclic AMP in rat mast cells during secretion of histamine induced by immunoglobulin E decapeptide and ACTH(1-24) peptide. Comparison with immunological and ionophore triggers.

D.S.Burt and D.R.Stanworth, Biochim. Biophys. Acta, 762, 458 (1983)

Prolonged corticotropic action of synthetic human ACTH in man.

G.Baumann and J.P.Felber, J. Clin. Endocrinol. Metab., 42, 160 (1976)

ACTH(1-24) stimulates the migration of human monocytes in vitro.

S.Genedani et al., Peptides, 11, 1305 (1990)

Expression and externalization of annexin 1 in the adrenal gland: structure and function of the adrenal gland in annexin 1-null mutant mice.

E.Davies et al., Endocrinology, 148, 1030 (2007)

Salt form: Trifluoroacetate

Molecular weight: 2933.48

Chemical Formula: C₁₃₆H₂₁₀N₄₀O₃₁S

Storage Temperature: < -15°C

Synonyms: Tetracosactide

One Letter code: SYSMEHFRWGKPVGKKRRPVKVYP

Source: Synthetic

Old Product Number: H-1150

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