Z-Phe-Arg-pNA · HCl

Z-Phe-Arg-pNA · HCl

Product Number: 4009170

CAS Number: 59188-54-4

€ 107 – € 428

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Product Description

Z-FR-pNA, a sensitive chromogenic substrate for cathepsin L and papain. Z-FR-pNA is also cleaved by falcipain 2. CAS Number (net): 117761-01-0.

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Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates.

T.Sasaki et al., J. Biol. Chem., 259, 12489 (1984)

2-amido-3-(1H-indol-3-yl)-N-substituted-propanamides as a new class of falcipain-2 inhibitors. 1. Design, synthesis, biological evaluation and binding model studies.

J.Zhu et al., Molecules, 14, 494 (2009)

Identification of a novel maturation mechanism and restricted substrate specificity for the SspB cysteine protease of Staphylococcus aureus.

I.Massimi et al., J. Biol. Chem., 277, 41770 (2002)

Structural and functional characterization of Falcipain-2, a hemoglobinase from the malarial parasite Plasmodium falciparum.

T.Hogg et al., J. Biol. Chem., 281, 25425 (2006)

Molecular weight: 612.09

Sum Formula: C₂₉H₃₃N₇O₆ · HCl

Storage Temperature: < -15°C

One Letter code: Z-FR-pNA · HCl

Source: Synthetic

Old Product Number: L-1242

Substrates
Cathepsin L
Papain
Falcipain II

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