(D-Arg¹,D-Pro²,D-Trp⁷·⁹,Leu¹¹)-Substance P

H-D-Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH₂

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Product Number: 4004685

CAS Number: 84676-91-5

€ 88.80

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Product Description

A potent antagonist for substance P and bombesin.

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Peptides in cancer research
Central administration of dipeptides, beta-alanyl-BCAAs, induces hyperactivity in chicks.

Y.Tsuneyoshi et al., BMC Neurosci., 8, 37 (2007)

Bombesin and bombesin antagonists: studies in Swiss 3T3 cells and human small cell lung cancer.

P.J.Woll and E.Rozengurt, Br. J. Cancer, 57, 579 (1988)

Effects of the substance P antagonist, (D-Arg1, D-Pro2, D-Trp7,9, Leu11)-SP on the miotic response to substance P, antidromic trigeminal nerve stimulation, capsaicin, prostaglandin E1, compound 48/80 and histamine.

A.Mandahl and A.Bill, Acta Physiol. Scand., 120, 27 (1984)

Molecular weight: 1497.81

Chemical Formula: C₇₅H₁₀₈N₂₀O₁₃

Storage Temperature: < -15°C

Synonyms: [DArg1, DPro2, DTrp7,9, Leu11] Substance P

One Letter code: rpKPQQwFwLL-NH₂

Source: Synthetic

Old Product Number: H-1930

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