(Nle⁴,D-Phe⁷)-α-MSH

Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂

Product Number: 4003800

CAS Number: 75921-69-6

€ 88.80 – € 356.30

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Product Description

Afamelanotide, a synthetic analog of α-MSH which shows prolonged biological activity and is 26 times more active than α-MSH in the adenylate cyclase assay.

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Peptides in cancer research
The Efficiency and Safety of Leuphasyl—A Botox-Like Peptide.

A.Dragomirescu et al., Cosmetics, 1, 75 (2014)

Skin pigmentation and pharmacokinetics of melanotan-I in humans.

S.O.Ugwu et al., Biopharm. Drug Dispos., 18, 259 (1997)

4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity.

T.K.Sawyer et al., Proc. Natl. Acad. Sci. USA, 77, 5754 (1980)

Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization.

M.E.Hadley and R.T.Dorr, Peptides, 27, 921 (2006)

Calcium-dependent prolonged effects on melanophores of [4-norleucine, 7-D-phenylalanine]-alpha-melanotropin.

M.E.Hadley et al., Science, 213, 1025 (1981)

K.R.Gehlsen et al., Pigment Cell Res., 5, 219 (1992)

Salt form: Trifluoroacetate

Molecular weight: 1646.87

Chemical Formula: C₇₈H₁₁₁N₂₁O₁₉

Storage Temperature: < -15°C

Synonyms: NDP-MSH

Source: Synthetic

Old Product Number: H-1100

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