Bz-Val-Gly-Arg-AMC

Bz-Val-Gly-Arg-AMC

Product Number: 4003312

CAS Number: 87779-49-5

€ 392.70 – € 1,569.70

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Product Description

Bz-VGR-AMC has been employed as substrate for the tricorn core protease from Thermoplasma acidophilum. Bz-VGR-AMC is used for measuring the trypsin-like activity of the 20S proteasome, in combination with e.g. Suc-LLVY-AMC (for assaying its chymotrypsin-like activity) and Z-LLE-AMC (for determining its PGPH activity).

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Action of rat liver cathepsin L on collagen and other substrates.

H.Kirschke et al., Biochem. J., 201, 367 (1982)

Proteasome inhibition measurements: clinical application.

E.S.Lightcap et al., Clin. Chem., 46, 673 (2000)

Navigation inside a protease: substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum.

J.S.Kim et al., J. Mol. Biol., 324, 1041 (2002)

The 20S proteasome isolated from Alzheimer's disease brain shows post-translational modifications but unchanged proteolytic activity.

F.Gillardon et al., J. Neurochem., 101, 1483 (2007)

Salt form: Trifluoroacetate

Molecular weight: 591.67

Sum Formula: C₃₀H₃₇N₇O₆

Storage Temperature: < -15°C

One Letter code: Bz-VGR-AMC

Source: Synthetic

Old Product Number: I-1085

Substrates
Proteasome Endopeptidase Complex

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