H-Leu-Ile-OH

H-Leu-Ile-OH

Product Number: 4002987

CAS Number: 36077-41-5

€ 142.30

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Product Description

According to Nitta et al. H-Leu-Ile-OH protects against neuronal death by inducing brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis. Alkam et al. observed that dietary supplementation with the hydrophobic dipeptide prevents the impairment of memory induced by amyloid β in mice via restraining the hyperphosphorylation of extracellular signal-regulated kinase. Leu-Ile forms nanotubes in the presence of D-leucine.

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Amyloid Beta Peptides & Alzheimer's Disease

Discovery of salt taste enhancing arginyl dipeptides in protein digests and fermented fish sauces by means of a sensomics approach.

A.Schindler et al., J. Agric. Food Chem., 59, 12578 (2011)

An analog of a dipeptide-like structure of FK506 increases glial cell line-derived neurotrophic factor expression through cAMP response element-binding protein activated by heat shock protein 90/Akt signaling pathway.

X.Cen et al., J. Neurosci., 26, 3335 (2006)

Hydrophobic dipeptide Leu-Ile protects against neuronal death by inducing brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis.

A.Nitta et al., J. Neurosci. Res., 78, 250 (2004)

Template-directed supramolecular assembly of a new type of nanoporous peptide-based material.

C.H.Görbitz and F.Rise, J. Pept. Sci., 14, 210 (2008)

Molecular weight: 244.33

Chemical Formula: C₁₂H₂₄N₂O₃

Storage Temperature: < -15°C

One Letter code: LI

Source: Synthetic

Old Product Number: G-2525

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