Tos-Arg-OMe · HCl

Tos-Arg-OMe · HCl

Product Number: 4002251

CAS Number: 1784-03-8

€ 107

Custom/Bulk Quote
Pack size available

25g
Please select pack size:
Add to your inquiry

Product Description

A good substrate for trypsin, thrombin, and urokinase as well as for plasma and glandular kallikreins. By competing for the arginine-binding site in the reactive center of proteases, L-TAME is also able to act as a reversible inhibitor. It suppresses, e.g., the TNF secretion of human leukocytes which is evidently dependent upon the action of serine proteases.

ADS
Example ADS
ADS lookup
ADS Lookup
MSDS
MSDS
MSDS lookup
MSDS Lookup
Requirement for metalloendoprotease in exocytosis: evidence in mast cells and adrenal chromaffin cells.

D.I.Mundy and W.J.Strittmatter, Cell, 40, 645 (1985)

Comparison of the catalytic properties of thrombin and trypsin by kinetic analysis on the basis of active enzyme concentration.

S.Takasaki et al., J. Biochem. (Tokyo), 78, 1275 (1975)

The action of thrombin on synthetic substrates.

S.Sherry and W.Troll, J. Biol. Chem., 208, 95 (1954)

Suppression of human leukocyte tumor necrosis factor secretion by the serine protease inhibitor p-toluenesulfonyl-L-arginine methyl ester (TAME).

P.Scuderi, J. Immunol., 143, 168 (1989)

Kallikrein concentrations in the plasma, lymph, thoracic, and cerebrospinal fluid of rabbits.

S.Naito et al., Arch. Int. Pharmacodyn., 252, 162 (1981)

Comparison of the catalytic properties of thrombin and trypsin by kinetic analysis on the basis of active enzyme concentration.

S.Takasaki et al., J. Biochem. (Tokyo), 78, 1275 (1975)

Kallikrein concentrations in the plasma, lymph, thoracic, and cerebrospinal fluid of rabbits.

S.Naito et al., Arch. Int. Pharmacodyn., 252, 162 (1981)

Action of various kallikreins and related enzymes on synthetic arginine and lysine derivatives as substrates.

Y.Matsuda et al., Chem. Pharm. Bull., 30, 1771 (1982)

Molecular weight: 378.88

Sum Formula: C₁₄H₂₂N₄O₄S · HCl

Storage Temperature: < -15°C

Synonyms: L-TAME

Old Product Number: M-1745

Substrates
Tissue Kallikrein
Plasma Kallikrein
Thrombin (Coagulation Factor IIa)
Trypsin
u-Plasminogen Activator
Clostripain

Country

Inquiry List

No products in the list

Discounts

SPECIAL
OFFERS

FAQ's

FAQs

ADS lookup

ADS Lookup

MSDS lookup

MSDS Lookup

Knowledge Center

Knowledge
Center