Bradykinin (1-5)

H-Arg-Pro-Pro-Gly-Phe-OH

Product Number: 4001554

CAS Number: 23815-89-6

€ 62.10 – € 249.30

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Product Description

The fragment RPPGF and the two dipeptides Phe-Arg and Ser-Pro are obtained by action of angiotensin-converting enzyme (ACE) on bradykinin. RPPGF inhibits thrombin-induced platelet activation, and in high concentration, the pentapeptide inhibits thrombin-induced coagulant activity.

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Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substrates.

M.Zimmerman et al., Anal. Biochem., 78, 47 (1977)

A metabolic fragment of bradykinin, Arg-Pro-Pro-Gly-Phe, protects against the deleterious effects of lipopolysaccharide in rats.

T.A.Morinelli et al., J. Pharmacol. Exp. Ther., 296, 71 (2001)

Mechanisms of Arg-Pro-Pro-Gly-Phe inhibition of thrombin.

A.A.K.Hasan et al., Am. J. Physiol. Heart Circ. Physiol., 285, H183 (2003)

Salt form: Trifluoroacetate

Molecular weight: 572.66

Sum Formula: C₂₇H₄₀N₈O₆

Storage Temperature: < -15°C

One Letter code: RPPGF

Source: Synthetic

Old Product Number: H-1945

Inhibitors
Thrombin (Coagulation Factor IIa)

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