H-Cys(Trt)-OH

H-Cys(Trt)-OH

Product Number: 4001485

CAS Number: 2799-07-7

€ 88.80 – € 267.50

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Product Description

Cys(Trt)-containing peptides can be converted in high yields into the corresponding cystine peptides by iodine oxidation. Cys(Trt) (STLC, NSC 83265) is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression.

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Peptides in cancer research

Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats.

K.Suetsuna et al., J. Nutr. Biochem., 15, 267 (2004)

On Cysteine and Cystine Peptides. I. New S-Protecting Groups for Cysteine.

L.Zervas and I.Photaki, J. Am. Chem. Soc., 84, 3887 (1962)

S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression.

D.A.Skoufias et al., J. Biol. Chem., 281, 17559 (2006)

Proteome analysis of apoptosis signaling by S-trityl-L-cysteine, a potent reversible inhibitor of human mitotic kinesin Eg5.

F.Kozielski et al., Proteomics, 8, 289 (2008)

R.G.Hiskey and J.B.Adams Jr., J. Org. Chem., 30, 1340 (1965)

M.N.Abualhasan et al., Eur. J. Med. Chem., 54, 483 (2012)

Molecular weight: 363.48

Chemical Formula: C₂₂H₂₁NO₂S

Storage Temperature: Room temperature

Synonyms: STLC

Old Product Number: E-2495

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