H-Glu-Trp-OH

H-Glu-Trp-OH

Product Number: 4000564

CAS Number: 38101-59-6

CHF 191.50 – CHF 573.50

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Product Description

A naturally occurring thymic immunomodulator. EW in vivo regulates NK cell function independent of IFNγ but partly dependent on IL-12. Substrate for aminopeptidase W, Km 0.49 mM and kcat 5557 min⁻¹ .

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Dipeptidyl-aminopeptidases and aminopeptidases in Dictyostelium discoideum.

S.A.T.Chan et al., Biochem. Biophys. Res. Commun., 127, 962 (1985)

Natural killer cell cytolytic activity is necessary for in vivo antitumor activity of the dipeptide L-glutamyl-L-tryptophan.

D.L.Smith et al., Int. J. Cancer, 106, 528 (2003)

Proteins of the kidney microvillar membrane. Enzymic and molecular properties of aminopeptidase W.

N.S.Gee and A.J.Kenny, Biochem. J., 246, 97 (1987)

The effects of the EW dipeptide optical and chemical isomers on the CFU-S population in intact and irradiated mice.

V.I.Deigin et al., Int. Immunopharmacol., 7, 375 (2007)

Proteins of the kidney microvillar membrane. Enzymic and molecular properties of aminopeptidase W.

N.S.Gee and A.J.Kenny, Biochem. J., 246, 97 (1987)

Molecular weight: 333.35

Sum Formula: C₁₆H₁₉N₃O₅

Storage Temperature: < -15°C

Synonyms: Oglufanide

One Letter code: EW

Source: Synthetic

Old Product Number: G-1990

Substrates
Aminopeptidase W

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