Met-Enkephalin

H-Tyr-Gly-Gly-Phe-Met-OH

Product Number: 4000010

CAS Number: 58569-55-4

 71.70 196.90

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Product Description

Opioid growth factor (OGF) and its receptor form a biological axis that tonically regulates cell proliferation by delaying the G1/S interface of the cell cycle under homeostatic conditions or in neoplasia. Exogenous OGF represses growth of human pancreatic cancer cells in culture and in nude mice. OGF therapy alone or in combination with standard chemotherapies results in enhanced inhibition of DNA synthesis and tumor growth.

I.S.Zagon and P.J.McLaughlin, World J. Gastroenterol., 20, 2218 (2014)

I.S.Zagon and P.J.McLaughlin, World J. Gastroenterol., 20, 2218 (2014)

R.N.Donahue et al., J. Cancer Ther., 2, 110 (2011)

Salt form: Acetate

Molecular weight: 573.67

Sum Formula: C₂₇H₃₅N₅O₇S

Storage Temperature: < -15°C

Synonyms: Endorphin (1-5)

One Letter code: YGGFM

Source: Synthetic

Old Product Number: H-2785

Inhibitors
Membrane Metalloendopeptidase
Tripeptide Aminopeptidase
Carboxypeptidase H

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