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Mca-Amyloid β/A4 Protein Precursor₇₇₀ (667-676)-Lys(Dnp)-Arg-Arg amide trifluoroacetate salt
Mca-Ser-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH₂ trifluoroacetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4033759.0001 1 mg Ships within 3-5 business days  
CHF 368.00
CHF 342.24 (7%)
4033759.0005 5 mg Ships within 3-5 business days  
CHF 1,471.00
CHF 1,368.03 (7%)


This fluorescent (FRET) peptide substrate contains the wild-type amyloid precursor protein (APP) β-secretase cleavage site. Mca-SEVKMDAEFRK(Dnp)RR- amide has been used for assaying β-secretase-like activity of thimet oligopeptidase (TOP, EC The results suggested that TOP is a potential β-secretase candidate and is involved in the processing of APP in vivo.
Catalog Number M-2460
APC Number 81-3-29
Synonyms Mca-APP₇₇₀ (667-676)-Lys(Dnp)-Arg-Arg amide
Molecular Formula C₈₇H₁₂₉N₂₇O₂₈S
Relative Molecular Mass 2033.21
CAS Registry Number 1802078-33-6
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Alzheimer's Disease


Enzyme Substrates Inhibitors
Thimet Oligopeptidase