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Details
The 33-amino acid neuropeptide neuromedin S (NMS) was originally isolated from rat brain as an endogenous ligand for two orphan G protein-coupled receptors FM-3/GPR66 and FM-4/TGR-1, which have been identified as neuromedin U (NMU) receptors. hNMS-33 is specifically expressed in the suprachiasmatic nuclei (SCN) of the hypothalamus. It has been shown that NMS is implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions.
Catalog Number
H-6232
One Letter Code
ILQRGSGTAAVDFTKKDHTATWGRPFFLFRPRN-NH₂
Synonyms
NMS (human)
Molecular Formula
C₁₇₃H₂₆₅N₅₃O₄₄
Relative Molecular Mass
3791.34
CAS Registry Number
1138204-27-9
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Obesity Research
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