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Nuclear Factor NF-KB Inhibitor SN50 trifluoroacetate salt
H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro-OH trifluoroacetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price
4037493.0500 0.5 mg Request lead time  
CHF 210.00
CHF 195.30 (7%)
4037493.1000 1 mg Request lead time  
CHF 368.00
CHF 342.24 (7%)


Nuclear Factor NF-KB Inhibitor SN50 is a cell-permeable nuclear translocation inhibitor of the transcription factor NF-KB. It consists of the hydrophobic region (h-region) of the Kaposi fibroblast growth factor (K-FGF) signal sequence which mediates the cellular import of this peptide and the nuclear localization signal (NLS) of the NF-KB p50 subunit. The peptide inhibited nuclear translocation of NF-KB in LPS- or TNF-α-stimulated murine endothelial LE-II and human monocytic THP-1 cells. In several cell lines SN50 interfered with NF-KB-mediated pro-apoptotic events such as caspase-3 activation.
Catalog Number H-6052
Synonyms Fibroblast Growth Factor-4 Precursor (7-22) (human)-Nuclear Factor NF-ΚB p105 Subunit (359-368) (human), FGF-4 Precursor (7-22) (human)-EBP-1 (359-368) (human), HST-1 Precursor (7-22) (human)-DNA-Binding Factor KBF1 (359-368) (human)
Molecular Formula C₁₂₉H₂₃₀N₃₆O₂₉S
Relative Molecular Mass 2781.54
CAS Registry Number 213546-53-3
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Growth Factors