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The deposition of α-synuclein (α-syn) fibrils in Lewy bodies is a characteristic feature of individuals with neurodegenerative disorders. The central hydrophobic region of α-synuclein, resembled by the peptide α-synuclein (71-82), is believed to be responsible for the protein aggregation. In addition, α-synuclein (71-82) forms amyloid fibrils of similar morphology to α-synuclein, suggesting that this region contributes to the fibrillogenic core of the full-length protein, referring to the studies of Madine and coworkers.
Catalog Number
H-8378
One Letter Code
VTGVTAVAQKTV
Molecular Formula
C₅₁H₉₂N₁₄O₁₇
Relative Molecular Mass
1173.36
CAS Registry Number
332867-16-0
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Alzheimer's Disease
Parkinson's Disease
Parkinson's Disease
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