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Availability: In stock

Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-m-nitro-Tyr-Asp-OH trifluoroacetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4026550.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 200.00
CHF 186.00 (7%)


Internally quenched fluorogenic peptide substrate containing anthranilic acid as fluorescent donor and m-nitro-tyrosine as acceptor (quencher). The sequence Abz-RVKRGLAY(NO₂)E is based on the sequence of hemagglutinin. The FRET substrate is efficiently cleaved by furin, a subtilisin-like eukaryotic serine endoprotease with Km = 3.8 µM and kcat = 29.3 s-¹ (kcat/Km = 7’710’000 M-¹s-¹). Its kcat/Km value is over 2000-fold higher than that of the commonly used substrate Boc-Arg-Val-Arg-Arg-AMC (I-1645). FRET Substrate for the basic residue-specific yeast aspartyl protease yapsin 1.
Catalog Number M-2115
APC Number 81-6-20
Synonyms Furin Substrate
Molecular Formula C₅₄H₈₄N₁₈O₁₆
Relative Molecular Mass 1241.37
CAS Registry Number 174838-79-0
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Furin substrate


Enzyme Substrates Inhibitors
Yapsin 1