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DABCYL-γ-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS trifluoroacetate salt

4031169

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4031169.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 547.00
CHF 508.71 (7%)
4031169.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 2,185.00
CHF 2,032.05 (7%)
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Details

The fluorogenic peptide substrate DABCYL-Abu-HPFHLVIHT-EDANS has been developed to continuously measure the proteolytic activity of human renin (Km = 1.5 µM at physiological pH). Cleavage of the FRET substrate occurs specifically at the Leu-Val bond and corresponds to the renin cleavage site of angiotensinogen. By means of this assay as low as 30 ng/mL renin can be detected after an incubation of only 3-5 min. Enzymatic cleavage yields the EDANS-fragment M-2645.
Catalog Number M-2050
One Letter Code DABCYL-Abu-HPFHLVIHT -EDANS
Molecular Formula C₉₀H₁₂₀N₂₂O₁₆S
Relative Molecular Mass 1798.15
CAS Registry Number [142988-22-5] net
Source Synthetic
Storage Conditions -20 ± 5 °C

4031169

Enzyme Substrates Inhibitors
Renin