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Availability: In stock

H-Asn-Glu-Ala-Tyr-Val-His-Asp-Ala-Pro-Val-Arg-Ser-Leu-Asn-OH

4030474

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4030474.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 158.00
CHF 146.94 (7%)
4030474.0005 5 mg Ships within 3-5 business days  
CHF 630.00
CHF 585.90 (7%)
4030474.0025 25 mg Ships within 3-5 business days  
CHF 2,521.00
CHF 2,344.53 (7%)
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Details

IL-1β converting enzyme (ICE, now called caspase-1), a cytosolic enzyme, is responsible for the cleavage of the inactive precursor protein to the active IL-1β. Similarly, caspase-1 hydrolyzes this 14-amino acid peptide that corresponds to the native cleavage site sequence around Asp¹¹⁶-Ala¹¹⁷. The peptide is also able to inhibit the cleavage of the precursor to the mature protein.
Catalog Number M-1890
APC Number 81-6-80
One Letter Code NEAYVHDAPVRSLN
Synonyms H-NEAYVHDAPVRSLN-OH, N-E-A-Y-V-H-D-A-P-V-R-S-L-N
Molecular Formula C₆₈H₁₀₅N₂₁O₂₃
Relative Molecular Mass 1584.71
CAS Registry Number [143305-11-7]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords ICE substrate
Areas of Interest Apoptosis & Necrosis

Product citations

J.R.Weidner et al., Peptides, Chemistry and Biology, Proceedings of the 12th American Peptide Symposium, Cambridge, MA, p. 891, J.A.Smith and J.E.Rivier, eds., Escom, Leiden, (1992)

4030474

Enzyme Substrates Inhibitors
Caspase-1 (ICE)