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Details
A good substrate for trypsin, thrombin, and urokinase as well as for plasma and glandular kallikreins. By competing for the arginine-binding site in the reactive center of proteases, L-TAME is also able to act as a reversible inhibitor. It suppresses, e.g., the TNF secretion of human leukocytes which is evidently dependent upon the action of serine proteases.
Catalog Number
M-1745
Synonyms
L-TAME
Molecular Formula
C₁₄H₂₂N₄O₄S · HCl
Relative Molecular Mass
378.88
CAS Registry Number
1784-03-8
EINECS Number
217-235-1
Storage Conditions
-20 ± 5 °C
Application
Hematology
Links / Documents:
Product citations
4002251
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Tissue Kallikrein | ||
| Plasma Kallikrein | ||
| Thrombin (Coagulation Factor IIa) | ||
| Trypsin | ||
| u-Plasminogen Activator | ||
| Clostripain |
