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Availability: In stock

Z-Leu-Arg-Gly-Gly-AMC acetate salt


Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4027157.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 378.00
CHF 351.54 (7%)


Z-LRGG-AMC is a fluorogenic substrate for isopeptidase T (IPaseT) and other ubiquitin C-terminal hydrolases (UCHs) based on the C-termini of ubiquitin with a kcat/Km value of 18 M⁻¹s⁻¹. Together with our product I-1690 it forms the basis of continuous assays for precise mechanistic studies or microtiter plate assays for high-throughput inhibitor screening. LRGG is the preferred substrate sequence of the human deSUMOylating enzymes SENP6 and 7. Stock solutions of Boc-LRGG-AMC are best prepared in DMSO.
Catalog Number I-1685
One Letter Code Z-LRGG-AMC
Molecular Formula C₃₄H₄₄N₈O₈
Relative Molecular Mass 692.77
CAS Registry Number 167698-68-2
Source Synthetic
Storage Conditions -20 ± 5 °C


Enzyme Substrates Inhibitors
Isopeptidase T    
Ubiquitinyl Hydrolase 1    
SENP6 Peptidase