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4031302

Availability: In stock

Mca-(endo-1a-Dap(Dnp))-TNF-α (-5 to +6) amide (human) trifluoroacetate salt
Mca-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH₂ trifluoroacetate salt

4031302

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4031302.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 263.00
CHF 244.59 (7%)
4031302.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,051.00
CHF 977.43 (7%)

Details

Mca-PLAQAV-Dpa-RSSSR-amide, a fluorogenic (FRET) peptide substrate for tumor necrosis factor (TNF) converting enzyme (TACE, ADAM-17 endopeptidase).
Catalog Number M-2255
APC Number 81-1-10
One Letter Code Mca-PLAQAV-Dpa-RSSSR-NH₂
Synonyms Mca-(endo-1a-Dap(Dnp))-TNF-a (-5 to +6) amide (human)
Molecular Formula C₆₉H₁₀₃N₂₃O₂₄
Relative Molecular Mass 1638.72
CAS Registry Number 192723-42-5
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords TACE substrate
Application Alzheimer's Disease
Cancer Research
Inflammation Research
Links / Documents:

Bachem product citations

A.R.Folgueras et al., J. Biol. Chem., 283, 9465 (2008)
U.Neumann et al., Anal. Biochem., 328, 166 (2004)
U.Neumann et al., Anal. Biochem., 328, 166 (2004)
H.I.Park et al., J. Biol. Chem., 275, 20540 (2000)

Product citations

M.E.Powers et al., Cell Host Microbe, 17, 775 (2015)
E.Parkin and B.Harris, J. Neurochem., 108, 1464 (2009)
D.E.Van Dyk et al., Bioorg. Med. Chem. Lett., 7, 1219 (1997)

4031302

Enzyme Substrates Inhibitors
Tumor Necrosis Factor (TNF) Convertase    
Matrix Metalloproteinase-12 (MMP-12)    
ADAM17 Endopeptidase    
ADAM10 Endopeptidase