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Availability: In stock

Boc-Val-Pro-Arg-AMC hydrochloride salt

4003460

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4003460.0050 50 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 315.00
CHF 292.95 (7%)
4003460.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1,261.00
CHF 1,172.73 (7%)
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Details

Boc-VPR-AMC, a specific, highly fluorogenic substrate for thrombin and the thrombin-staphylocoagulase complex. The thrombin assay has been used for the indirect determination of coagulation factor III. Trypsin, tryptase from rat mast cells, and two trypsin-like enzymes from sperm of the ascidian Halocynthia roretzi, acrosin and spermosin, also hydrolyze this substrate. Furthermore, Boc-VPR-AMC is cleaved by the Kex2 endoprotease (kexin, previously known as proteinase yscF), a membrane-bound, calcium-dependent serine protease from yeast α-cells.
Catalog Number I-1120
Molecular Formula C₃₁H₄₅N₇O₇
Relative Molecular Mass 627.74
CAS Registry Number [65147-04-8] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Hematology

Bachem product citations

J.van Soom et al., MedChemComm, 6, 1954 (2015)

4003460

Enzyme Substrates Inhibitors
Kexin    
Thrombin (Coagulation Factor IIa)    
Trypsin    
Tryptase