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SPLUNC1 (22-39) trifluoroacetate salt
H-Gly-Gly-Leu-Pro-Val-Pro-Leu-Asp-Gln-Thr-Leu-Pro-Leu-Asn-Val-Asn-Pro-Ala-OH trifluoroacetate salt

4081062

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4081062.0500 0.5 mg Ships within 3-5 business days  
CHF 128.00
CHF 119.04 (7%)
4081062.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 214.00
CHF 199.02 (7%)
4081062.5000 5 mg Ships within 3-5 business days  
CHF 857.00
CHF 797.01 (7%)
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Details

SPLUNC1 is an endogenous inhibitor of the epithelial sodium channel (ENaC) which is responsible for Na⁺ and fluid absorption across colon, kidney, and airway epithelia. The partial sequence GGLPVPLDQTLPLNVNPA (SPLUNC1 22-39) corresponds to the ENaC inhibitory domain of SPLUNC1. As ENaC hyperactivity contributes to the development of cystic fibrosis in the lungs, the fragment could help to develop new strategies for the treatment of this genetic disorder.
Catalog Number H-7352
One Letter Code GGLPVPLDQTLPLNVNPA
Molecular Formula C₈₂H₁₃₅N₂₁O₂₅
Relative Molecular Mass 1815.10
CAS Registry Number [1421132-47-9] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Ion Channel Modulating Agents